吴谦，男，2015年上海交通大学博士毕业，博士阶段主要从事多种分析技术的肺癌代谢组学研究。江南大学食品学院硕士研究生校外合作导师。曾担任上海生物信息技术研究中心副研究员；“质谱关键技术研发与临床应用安徽省联合共建学科重点实验室”负责人。曾在恒瑞医药参与十余个一类新药项目及部分重组蛋白药物研发，其中硫培非格司亭（19K）、瑞格列汀等已获批上市。承担或参与上海市自然科学基金、国家自然科学基金、国家重大科学仪器设备开发专项、上海市科委项目等多个项目。在Journal of Proteomics、Phytomedicine、Analytical Chemistry等杂志发表论文28篇，授权发明专利5项。

研究方向为蛋白质组学，代谢组学/脂质组学方法学开发及其在肿瘤、心血管疾病、传染病等诊断标志物筛选中的应用；临床质谱新技术；多组学联合分析等。

1      Jia-Yi Weng, Jia-Yu Yang, Ishimwe Steven Papy, Bu-Tao Yu, Yu-Feng Ke, Bing-Yu Bai, Mitchell N. Muskat, Qian Wu*, Xiang-Rong Cheng*, Cinnamaldehyde alleviates hepatic steatosis correlating with its electrophilic capability. Food Bioscience. 2024, 59:104142.

2      Ni Yiming#, Wang Xin#, Wu Qian#, Yao Yichen, Xu Yuan, Li Yuanyuan, Feng Qin, Zhou Mingmei*, Gou Xiaojun*. Qushi Huayu decoction ameliorates non-alcoholic fatty liver disease in rats by modulating gut microbiota and serum lipids. Frontiers in Endocrinology. 2023, 14:1272214.

3      Qian Wu#, Yuanyuan Huang#, Xiangya Kong#, Ben Jia, Xiaoting Lu, Yunqin Chen, Zechi Huang*, Yuan-Yuan Li*, Wentao Dai*. DBLiPro: A Database for Lipids and Proteins in Human Lipid Metabolism. Phenomics. 2023, 34:350-359.

4      Shi-Ang Qi#, Qian Wu#, Zhenpu Chen, Wei Zhang, Yongchun Zhou, Kaining Mao, Jia Li, Yuanyuan Li, Jie Chen*, Youguang Huang*, Yunchao Huang*. High-resolution metabolomic biomarkers for lung cancer diagnosis and prognosis. Scientific Reports. 2021, 111:11805.

5      Dezhi Xie#, Jiayan Wu#, Qian Wu#, Xiaojun Zhang, Danya Zhou, Wentao Dai, Mengting Zhu, Dian Wang*. Integrating proteomic, lipidomic and metabolomic data to construct a global metabolic network of lethal ventricular tachyarrhythmias LVTA induced by aconitine. Journal of Proteomics. 2021, 232:104043.

6      Yiwen Hu, Qian Wu, Yang Qiao, Peng Zhang, Wentao Dai, Hongyue Tao*, Shuang Chen*. Disturbances in Metabolic Pathways and the Identification of a Potential Biomarker Panel for Early Cartilage Degeneration in a Rabbit Anterior Cruciate Ligament Transection Model. Cartilage. 2021, 132_suppl:1376S-1387S.

7      Shi-yuan Wen#, Yan-yan Chen#, Jia-xi Lu, Qian-qian Liang, Hong Shi, Qian Wu*, Zhi-hong Yao, Yan Zhu, Miao-miao Jiang*. Modulation of hepatic lipidome by rhodioloside in high-fat diet fed apolipoprotein E knockout mice. Phytomedicine. 2020, 69: 152690.

8      Yang Zhang#, Chenchen Li#, Chuanzhen Hu, Qian Wu, Yongping Cai, Songge Xing, Hui Lu, Lin Wang, De Huang, Linchong Sun, Tingting Li, Xiaoping He, Xiuying Zhong, Junfeng Wang, Ping Gao, Zachary J Smith, Weidong Jia*, Huafeng Zhang*. Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1. EMBO Reports. 2019, 20: e48115.

9      Jiayan Wu#, Yongping Zhang#, Qian Wu#, Dezhi Xie, Wentao Dai, Xiaojun Zhang, Zhuo Yang, Dian Wang*. Integrative analyses of myocardial lipidome and proteome implicate mitochondrial dysfunction in lethal ventricular tachyarrhythmia LVTA induced by acute myocardial ischemia AMI. Journal of Proteomics. 2019, 197:14-22.

10   Qian Wu, Xinwei Yu, Yan Wang, Xue Gu, Xiaoqiong Ma, Wang Lv, Zhe Chen, Chao Yan*. Pressurized CEC coupled with QTOF-MS for urinary metabolomics. Electrophoresis. 2014, 35:2470-2478.