郑培义，2013年毕业于合肥工业大学生物工程专业，获得学士学位。2019年毕业于中国科学技术大学生物化学与分子生物学专业，获得博士学位，研究方向为结构生物学。2020年-2024年在中国科学技术大学生命科学与医学部从事博士后研究。2024年7月加入大健康研究院公共卫生与生物安全研究所金腾川教授课题组从事副研究员工作。以第一/共同第一作者身份在CELL RES、J CLIN INVEST、INT J BIOL MACROMOL、J MOL BIOL 等期刊发表论文多篇。

1、针对肿瘤关键靶点的治疗性抗体药物开发。

2、病原微生物感染宿主细胞的入侵机制研究及相关疾病的抗体药物开发。

1.  Yulei Chen*; Xinxin Xie*; Peiyi Zheng*; Chenchen Zhu; Huan Ma; Zunera Khalid; Yangjie Xie; Yizhao Dang; Yaxin Ye; Nengyin Sheng; Ning Zhong; Wenhui Lei; Changgong Zhang; Lingjing Zhang; Tengchuan Jin#; Minjie Cao# ; Selection, identification and crystal structure of shark-derived single-domain antibodies against a green fluorescent protein, International Journal of Biological Macromolecules, 2023, 30247: 125852

2.  Yiyu Chen; Tengchuan Jin; Mengsi Li; Xiao Yun; Fei Huan; Qingmei Liu; Mengjun Hu; Xiaofeng Wei; Peiyi Zheng#; Guangming Liu# ; Crystal Structure Analysis of Sarcoplasmic-Calcium-Binding Protein: An Allergen in Scylla paramamosain, Journal of Agricultural and Food Chemistry, 2023, 712: 1214-1223

3. Jia Zou*#; Li Li*; Peiyi Zheng*; Wenhua Liang*; Siyi Hu*; Shuaixiang Zhou*; Yanqun Wang*; Jincun Zhao*; Daopeng Yuan; Lu Liu; Dongdong Wu; Mengqiu Xu; Fangfang Zhang; Mengzhu Zhu; Zhihai Wu; Xiaochao Cao; Meng Ni; Xiaomin Ling; Yue Wu; Zhihui Kuang; Moyan Hu; Jianfeng Li; Xue Li; Xiling Guo; Tianmin Xu; Haiping Jiang; Changshou Gao; Michael Yu; Junjian Liu; Nanshan Zhong; Jianfeng Zhou#; Jian-An Huang#; Tengchuan Jin#; Jianxing He# ; Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance, Journal of Clinical Investigation, 2022, 1324: e154987

4. Huan Ma*; Xinghai Zhang*; Peiyi Zheng*; Peter H. Dube*; Weihong Zeng*; Shaohong Chen*; Qingyu Cheng; Yunru Yang; Yan Wu; Junhui Zhou; Xiaowen Hu; Yan Xiang#; Huajun Zhang#; Sandra Chiu#; Tengchuan Jin#; Hetero-bivalent nanobodies provide broad-spectrum protection against SARS-CoV-2 variants of concern including Omicron, Cell Research, 2022, 329: 831-842

5. Peiyi Zheng; Mengying Zhang#; Muhammad Hidayatullah Khan; Hejun Liu; Yuping Jin; Jian Yue; Yongxiang Gao; Maikun Teng; Zhongliang Zhu#; Liwen Niu#; Crystallographic Analysis of the Catalytic Mechanism of Phosphopantothenoylcysteine Synthetase from Saccharomyces cerevisiae, Journal of Molecular Biology, 2019, 4314: 764-776