李叔航，女，2021年12月博士毕业于中国科学技术大学生命科学学院；2022年1月-2024年2月在中国科学技术大学从事博士后研究工作；2024年3月加入大健康研究院先进医药与再生医学研究所白丽课题组，从事抗肿瘤的免疫治疗新药物和新方案的开发工作。参与的项目成果发表在SCI期刊6余篇，其中以第一作者或共第一作者身份发表3篇（Journal of Experimental Medicine、Biology of Reproduction、Reproductive Toxicology）。参与授权的国内专利1项。主持国家自然科学基金青年项目，并参与科技部重点研发计划等项目。

通过探索iNKT细胞的功能调控机制以及与慢性炎症、肿瘤等疾病的关系，发现并验证干预iNKT细胞功能的新靶点和新策略，为慢性炎症、肿瘤等疾病的免疫治疗提供新药物和新方案。

1.  Shuhang Li, Linlin Wang, Zhihao Xu, Yuanyuan Huang, Rufeng Xue, Ting Yue, Linfeng Xu, Fanwu Gong, Shiyu Bai, Qielan Wu, Jiwei Liu, Bolong Lin, Huimin Zhang, Yanhong Xue, Pingyong Xu, Junjie Hou, Xiaofei Yang, Tengchuan Jin, Rongbin Zhou, Jizhong Lou, Tao Xu, Li Bai*. ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activation. Journal of Experimental Medicine, 2021, 2189.

2. Rufeng Xue#,*, Shuhang Li#, Huijuan Zou, Dongmei Ji, Mingrong Lv, Ping Zhou, Zhaolian Wei, Zhiguo Zhang*, Yunxia Cao*. Melatonin alleviates deoxynivalenol-induced apoptosis of human granulosa cells by reducing mutually accentuated FOXO1 and ER stress. Biology of Reproduction, 2021, 1052:554-566.

3. Rufeng Xue#,*, Shuhang Li#, Zhaolian Wei, Zhiguo Zhang, Yunxia Cao*. Melatonin attenuates di-2-ethylhexyl phthalate-induced apoptosis of human granulosa cells by inhibiting mitochondrial fission. Reproductive Toxicology, 2022, 113:18-29.

4. Shiyu Bai#, Qielan Wu, Shasha Zhu, Yuwei Zhang, Xuran Chen, Miya Su, Jun Pan, Shuhang Li, Ting Yue, Linfeng Xu, Di Xie, Chenxi Tian, Dan Zhao, Xiang Li, Junjie Hou, Lu Wang, Sicheng Fu, Yanhong Xue, Amin Jiang, Dong Li, Tao Xu, Zhigang Tian, Rongbin Zhou, Huimin Zhang, Li Bai*. Vam6 reduces iNKT cell function in tumor via modulating AMPK/mTOR pathways. Frontiers in Immunology. 2023, 19;13:1051045

5. Qielan Wu, Shiyu Bai, Miya Su, Yuwei Zhang, Xuran Chen, Ting Yue Linfeng Xu, Lu Wang, Di Xie, Shuhang Li, Xiang Li, Sicheng Fu, Lili Wang, Chenxi Tian, Jun Pan, Yuanyuan Huang, Yuting Cai, Yu Wang, Fang Hu, Fengyin Li, Huimin Zhang, Li Bai*. HIVEP3 inhibits fate decision of CD8+ invariant NKT cells after positive ion. Journal of Leukocyte Biology. 2023, 27;1144:335-346.

6. Chenxi Tian, Yu Wang, Miya Su, Yuanyuan Huang, Yuwei Zhang, Jiaxiang Dou, Changfeng Zhao, Yuting Cai, Jun Pan, Shiyu Bai, Qielan Wu, Sanwei Chen, Shuhang Li, Di Xie, Rong Lv, Yusheng Chen, Yucai Wang, Sicheng Fu, Huimin Zhang, Li Bai*. Motility and tumor infiltration are key aspects of invariant natural killer T cell anti-tumor function. Nature Communications. 2024, 15:1213